In CP CML hematopoietic (CD34+) cells transduced with lentiviral-ADAR1 and co-cultured with humanized mouse stromal cells that recapitulate the bone marrow microenvironment [25] (Figure 4A), ADAR1 expression levels were variable across samples, with one sample displaying very high expression of ADAR1 after lentiviral-ADAR1 transduction (Figure 4B,C). Here, CD34 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.