After adjusting for age, sex and DD, the partial correlations analyses demonstrated strongly positive correlations of UUAE levels with SBP, DBP, BMI, WHR, FPG, 2 h PPG, FCP, 2 h PCP, HOMA2-IR, TTG, TC, ALT, eGFR, and CRP, and significantly negative correlations between UUAE levels and age (controlling for sex and DD), DD (controlling for age and sex), HOMA2 %S, HDL-C, Cr, and UAE in diabetics. The gene discussed is CRP; the disease is diabetes mellitus.