In our previous study, we tested the supernatant from adipose tissue-derived MSCs (ATMSCs) and cytotoxic T-lymphocyte antigen 4 (CTLA4)-overexpressing ATMSCs (CTLA4-ATMSCs) for suppressive effects on the proliferation of peripheral blood mononuclear cells (PBMCs) from dogs with experimental autoimmune thyroiditis. The gene discussed is CTLA4; the disease is autoimmune thyroid disease.