IFNG and dacryoadenitis: To confirm the role of IFN-γ in promoting glandular apoptosis in the CD25KO model, we evaluated caspase activity in LG protein lysates and performed TUNEL assay in CD25/IFN-γ DKO LG cryosections at 4 W and 8 W. These mice have significantly delayed and less severe dacryoadenitis compared to CD25KO mice at 8 W [10].