PINX1 and breast cancer: The univariate Cox regression analyses revealed that PinX1 expression was an independent prognostic marker for breast cancer patients overall survival (hazard ratio, 0.573; 95% CI, 0.371-0.884; P = 0.012; Table 2) and disease-specific survival (hazard ratio, 0.417; 95% CI, 0.230-0.755; P = 0.004; Table 2).