In a metastatic model of murine EOC using intraperitoneal (i.p.)administration of syngeneic mouse ovarian surface epithelial cancer cells (MOSEC-ID8), we previously observed that granulocytic MDSCs (CD11b+Ly6G+Ly6Clow) accumulated in the peritoneum as a function of tumor burden, and suppressed stimulated T cell proliferation, while non-myeloid (CD11b−) peritoneal cells from tumor-bearing mice either incompletely suppressed or had no effect on stimulated T cell proliferation ex vivo [11]. The gene discussed is ITGAM; the disease is neoplasm.