Western blot results indicated that MORC2 S677A mutation attenuated the phosphorylation of MORC2 on serine 677 in Flag-MORC2/SGC-7901 cells (an exogenous MORC2 stable expression gastric cancer cell line, see Figure 1D) compared with wild-type MORC2 (MORC2-WT). The gene discussed is MORC2; the disease is gastric cancer.