VEGFA and myocardial infarction: A study has shown that IL-10 knockout (KO) mice reduce myocardial-infarction (MI)-induced mobilization of bone marrow EPCs, down-regulate the expression of CXCR4 and VEGF, and enhance the susceptibility to inflammation or hypoxia-induced apoptosis, which can be reversed by systemic IL-10 therapy [21].