CXCR4 and brain ischemia: Consequently, the main aspects are as follows: in terms of physical therapy, it has been reported that electroacupuncture of the specific acupoints known as “Quchi” and “Zusanli” can up-regulate levels of EPCs from peripheral blood and bone marrow, serum total NOS activities, VEGF levels, blood CXCR4+ cells, as well as blood SDF-1alpha protein content in cerebral ischemia/reperfusion injury rats, which may help alleviate injury, promote neovascularization, and improve cerebral ischemia [78-80].