Krishnamurthy et al. [21] indicated that mobilization of EPCs following MI is impaired in IL-10 KO mice; conversely, IL-10 increases the survival and function of EPCs, possibly through activating STAT3/VEGF signaling pathways, to further weaken MI-induced left ventricular dysfunction and remodeling. The gene discussed is IL10; the disease is myocardial infarction.