The peri-implantitis group showed a significantly greater level of IL-6 than the healthy group (0.96 ± 0.64 and 0.53 ± 0.63 respectively, p < 0.01); IL-1β (58.5 ± 84.8 and 21.2 ± 24.2 respectively, p < 0.01); IL-10 (0.91 ± 0.90 and 0.45 ± 0.87 respectively, p < 0.05); TNF- α (1.08 ± 1.49 and 0.25 ± 0.56 respectively, p < 0.01) (Figures 3 and 4). This evidence concerns the gene IL6 and Peri-Implantitis.