TLR2 and pulmonary fibrosis: Kim and colleagues have indicated that the TLR2-mediated production of IL-27 and chemokines by respiratory epithelial cells promotes bleomycin (BLM)-induced pulmonary fibrosis (BIPF) in mice, In addition, BIPF was more severe in IL-17A−/− mice and in TLR2−/− mice treated with an anti–IL-17 monoclonal antibody than in TLR2−/− and wild-type (WT) mice [11].