ENO1 and neoplasm: Mice were sacrificed 15 days after inoculation, with average tumor weights of 0.059 ± 0.016 vs 0.73 ± 0.12 g in PLV-Ctr vs A549-ENO1 group and 0.95 ± 0.13 vs 0.435 ± 0.051 g in PLV-shCtr vs shENO1-B group, respectively (P < 0.01) (Figure 3E).