Liu et al. [33,34] reported that GA alone did not increase expression of CHOP and GRP78 but the combination of GA and calcium channel blocker verapamil or proteasome inhibitors bortezomib, induced high expression of these two proteins especially CHOP protein in human hepatoma HepG2 and leukemia K562 cells. The gene discussed is HSPA5; the disease is hepatocellular carcinoma.