Although results for BRINP3 exon 2–3 primers expression were not statistically significant, a similar trend of higher expression in diseased tissues compared to healthy tissues (p = 0.06) and in individuals with both peri-implant disease and chronic periodontitis compared to tissues from individuals with peri-implantitis only (p = 0.07), could be seen. The gene discussed is BRINP3; the disease is periodontitis.