CD8A and neoplasm: A kinetic study was undertaken in which CFSE-labelled, CD8+ T cells prepared from the lymph nodes and spleens of OT-1 mice were adoptively transferred into recipient mice bearing either AE17 tumors (the negative control) or AE17sOVA tumors which express ovalbumin as a marker, or spy, tumor antigen and to which OT-1 T cells will respond by proliferating if the antigen is appropriately presented to them by local DCs [16].