In fact, increased levels of proteins modified by HOCl generated by the MPO/H2O2/Cl− system have been found in serum of HD patients, such as oxidized albumin; HOCl-modified albumin impairs the association of high-density lipoprotein (HDL) with the scavenger receptor class B type I, which have a protective role against atherosclerotic cardiovascular disease [45]; also, it was found a direct relationship between plasma levels of oxidized low density lipoprotein (ox-LDL) and MPO in CKD diabetic patients during HD [46]. The gene discussed is ALB; the disease is Huntington disease.