Some stated that hematological changes are unreliable laboratory indicators of malaria in acute uncomplicated P. falciparum malaria [49], while others reported that lower level of some hematological parameters such as platelet, WBCs, and lymphocyte counts WBCs, eosinophils, RBCs and Hb level when used in combination with other clinical and parasitological method could be the most important predictors of malaria infection [50-53]. Here, GSTM1 is linked to malaria.