Thus, also in this experimental situation the NX group had a downward shift of the Ca recovery curve from acute hypocalcemia, once again providing further support for the existence of a rapid effect of NX on the set-point for Ca2+, which is independent of PTH and CT, although it still is respecting the degree of hypercalcemia, which developed post TPTX. The gene discussed is PTH; the disease is hypercalcemia disease.