An impact of C-terminal PTH fragments and/or CT on the rapid decline of plasma Ca2+ in acute uremia, as previously hypothesized from our lab, could however not be confirmed by the results of the present investigation, as no influence of PTH, C-terminal PTH and CT was found on plasma Ca2+ concentrations when comparing the models of TPTX (without PTH and CT) and NX-TPTX rats (without PTH, CT and kidneys). Here, PTH is linked to uremia.