Mutations in this gene are of practical relevance to malaria-infected individuals for two main reasons; On one hand G6PD-deficiency is believed to be associated with susceptibility or resistance to malarial disease while on the other hand, certain oxidative anti-malarial drugs (i.e. primaquine and sulphur containing drugs) can trigger haemolytic anaemia [7-9], which is of practical concern to all malaria endemic countries including Sri Lanka. This evidence concerns the gene G6PD and malaria.