A significant association between a high miR-200c blood level and poor PFS (HR 3.33; 95% CI: 1.22 to 9.07; P = 0.019) and OS (HR 2.79; 95% CI: 1.01 to 7.7); P = 0.048) was found, with independence of tumour stage and hormonal receptors status as depicted (Figure 5A). This evidence concerns the gene NR4A1 and neoplasm.