Results are plotted in Fig 4, which shows that LN229 glioblastoma growth was most sensitive to the production of HIF1α (k8) production of IGFBP2 (k1), growth rate due to HIF1α (k11) and promotion of HIF1α by IGFBP2 (k10). Here, IGFBP2 is linked to glioblastoma.