The Mann–Whitney U test was used to evaluate differences between the absolute values of urinary DiAcSpm and serum CEA level (≤5.0 mg/dL vs. >5.0 mg/dL), lymph node metastasis (N0 vs. N1-2), vascular invasion (positive vs. negative), lymphatic permeation (positive vs. negative), histological type (adenocarcinoma vs. others), tumor size (≤2.0 cm vs. >2.0 cm), and TDR (≥0.75 vs. <0.75). This evidence concerns the gene CEACAM5 and neoplasm.