The children of GCA had a higher allele frequencies of ITGA5-1160 T-carrier (79% vs. 65%; P = 0.006), ITGB-1949 A-carrier (84% vs. 74%; P = 0.047), ITGB1 + 31804 C-carrier (95% vs. 88%; P = 0.013), IL-10-819 TT (52% vs. 38%; P = 0.014), IL-10-592 AA (52% vs. 38%; P = 0.014) and COX-2-1195 G-carrier (83% vs. 71%; P = 0.019), as compared with DU controls. This evidence concerns the gene ITGB1 and temporal arteritis.