Bcl-2 expression correlated negatively with that of TLR3 (γ = −0.369, P < 0.01), TRIF (γ = −0.288, P < 0.01), and IRF3 (γ = −0.236, P < 0.05) in HCC tissue samples (Table 4). This evidence concerns the gene IRF3 and hepatocellular carcinoma.