CASP3 and hepatocellular carcinoma: Using immunohistochemistry, we detected the cytoplasmic expression of the apoptosis-related proteins survivin, Bcl-2, and caspases 3, 8, and 9 (Figure 3), which were expressed in 48.2% (41/85), 38.8% (33/85), 71.8% (61/85), 68.2% (58/85) and 57.6% (49/85), respectively, of HCC tissue samples.