BRCA1 and cancer: Although mean age of cancer diagnosis of BRCA1 mutation carriers (53.8 years, range 36 – 76 years) was lower than BRCA2 mutation carriers (58.5 years, range 48 – 74 years) and women without mutations (61.3 years, range 24 – 91 years), this difference in age at diagnosis was not statistically significant, although this statistical analysis may have been limited by the small sample sizes for each comparison group.