Of these 53 tumour samples, 13 (all NSCLC, 24.5%) showed TP53 mutations (9 missense mutations and 4 deletions), while 40 (39 NSCLC and 1 SCLC, 75.5%) showed no mutation; the median rate of tumour cells with p53 overexpression in tumours with mutations was 60%, while in tumours without mutations was 40% (p = 0.04). The gene discussed is TP53; the disease is non-small cell lung carcinoma.