TP53 and neoplasm: Finally, we did not find a significant correlation between positive levels of serum p53Abs and TP53 mutations in the corresponding tumours, nor between TP53 mutations and clinicopathologic features, presumably due to the small number of suitable tumour samples, while a significant correlation between TP53 mutations and tumours with the highest median rate of p53 overexpression was observed within the p53 protein-positive tumour samples (p = 0.04).