Furthermore, a significant correlation between high levels of p53 protein expression and squamous cell carcinoma compared to adenocarcinoma was observed (p = 0.008), while no difference was found with regard to NSCLC stage (Table 6); p53 overexpression was also significantly associated with NSCLC of highest grade (p = 0.012). The gene discussed is TP53; the disease is squamous cell carcinoma.