The AUC to diagnose established normoalbuminuric, microalbuminuric and macroalbuminuric type 2 diabetes using urine periostin were 0.78 (95%CI, 0.71 to 0.86), 0.99 (95%CI, 0.98 to 1.00) and 0.95 (95%CI, 0.91 to 0.98), respectively. The gene discussed is POSTN; the disease is type 2 diabetes mellitus.