Endogenous AR activity was measured in vehicle- and androgen-treated AD-LNCaP cells co-transfected with the androgen-responsive probasin-luciferase expression vector and increasing amounts of the CXCR7-SBP expression vector (30 ng, 100 ng, and 300 ng; Figure 6A) [53]. The gene discussed is AR; the disease is Alzheimer disease.