Vascular cell adhesion molecule-1 (VCAM1), a member of the immunoglobulin superfamily of adhesion molecules which is up-regulated in response to tumor necrosis factor-alpha, IL-1 and lipopolysaccharide, plays key roles in various stages of tumor angiogenesis and is also involved in tumor progression and metastasis [37, 38]. This evidence concerns the gene VCAM1 and neoplasm.