While comparison of WNV strains has been previously performed in DCs to show that WNV strains with glycosylated envelope (E) protein have increased infection and replication rates [14], WNVNY99 and WNVNSW2011 both have glycosylated E [4], and are therefore expected to be equally efficient in viral entry into MoDCs through attachment to DC-SIGN or DC-SIGNR receptors [11]. This evidence concerns the gene CD209 and infection.