In the present study, the BRAF mutation frequency (23%) was higher compared to the 5-17% previously reported in colorectal cancer [30,32,41], possibly explained by the fact that right-sided tumours were predominant in our cohort and BRAF mutations have been reported to mainly occur in tumours of the right colon [30,37,39-41]. The gene discussed is BRAF; the disease is colorectal cancer.