As MSLN is highly expressed in various human tumors, our findings suggest that MSLN-specific imaging using 64Cu-labeled 11-25 mAb has the potential to be widely used in the diagnosis of patients with MSLN-positive cancers such as malignant mesotheliomas and ovarian cancers and pancreatic cancers. The gene discussed is MSLN; the disease is familial pancreatic carcinoma.