TNC and myocardial infarction: In patients with acute myocardial infarction, peak serum TNC level at 5 days after infarction is an important independent predictor of prognosis, and higher TNC level is associated with a greater risk of left ventricular remodeling at 6 months after infarction, indicating that overexpression of TNC may aggravate ventricular remodeling [16].