One study by K. Raafat and W. Samy titled “Amelioration of Diabetes and Painful Diabetic Neuropathy by Punica granatum L. Extract and Its Spray Dried Biopolymeric Dispersions” describes the effect of ethanol extract (Pg), casein/Pg dispersion (F1), chitosan/Pg dispersion (F2), and gallic acid (GA) on diabetes and related neuropathy in mice treated with alloxan. Here, JUP is linked to diabetic neuropathy.