HBEGF and Sepsis: In addition, FGFβ (802.3 ± 402.9 versus 1,573.4 ± 456.9 ng/mL; P <0.012), IL-15 (38.6 ± 23.1 versus 256.1 ± 128.7 ng/mL; P <0.031), MCP-3 (22.4 ± 4.6 versus 93.9 ± 33.0 ng/mL; P <0.011), HB-EGF (21.2 ± 7.8 versus 642.0 ± 254.4 ng/mL; P <0.044), and KGF (33.7 ± 9.8 versus 177.1 ± 103.0 ng/mL; P <0.046) were also significantly up-regulated in the plasma of severe sepsis patients, but not included in the cytokine mixtures.