In order to systematically check whether the SH2B3‐derived PPI subnetwork showed any enrichment for literature‐based BP‐related genes, we created a list of 657 BP‐related genes by searching GeneRif (http://www.ncbi.nlm.nih.gov/gene/about-generif; downloaded in Jan 2015) using the keywords ‘hypertension’ and ‘blood pressure’. The gene discussed is SH2B3; the disease is Hypertension.