Several additional BP signature genes have been reported to be involved in BP‐related diseases or processes such as cardiovascular disease (e.g., ABCA1 (Tang & Oram, 2009), AHR (Zhang, 2011), and GZMB (Joehanes et al, 2013a,b)), type II diabetes (e.g., ABCA1 (Tang & Oram, 2009), ANXA1 (Lindgren et al, 2001), and PTGS2 (Shanmugam et al, 2006)), and inflammation (e.g., GZMB (Hiebert & Granville, 2012) and KLRD1 (Choi et al, 2012)). This evidence concerns the gene ANXA1 and type 2 diabetes mellitus.