IKBKB and neoplasm: Interestingly, low-IKKβ and low-p53 mRNA tumours was more frequently observed in p53-WT patients (P = 0.016 for IKKβ; P = 0.017 for p53), but the opposite was seen in p53-mutant patients (P = 0.002 for IKKβ; P = 0.003 for p53).