CTSE and Parkinson disease: Here we determined the specific activity of several endo-lysosomal enzymes, namely β-hexosaminidase, α-fucosidase, β-mannosidase, α-mannosidase, β-galactosidase, β-glucocerebrosidase and cathepsin E, in different brain areas of PD patients, age-matched controls and, for some brain areas, of patients diagnosed with dementia with Lewy bodies (DLB).