NQO1 and familial pancreatic carcinoma: Furthermore, we also found that NQO1 protein was frequently high-expressed in gastric adenocarcinoma compared with the gastric dysplasia and adjacent non-tumor tissues, indicating that NQO1 was a significant prognostic or predictive maker of gastric adenocarcinoma [24]. Consistently, Awadallah et al. [25] and Lyn-Cook et al. [26] reported that NQO1 protein was up-regulated in pancreatic ductal adenocasinoma, and also considered that NQO1 may represent a role of useful biomarker for pancreatic cancer.