In the 13 SNPs, only rs662 and rs705379 in PON1 were close to be significantly associated with carotid plaque score in post-RT NPC patients (rs662, Pcor = 0.0842 in additive model and Pcor =0.0528 in dominant model; and rs705379, Pcor = 0.0842 in additive and dominant models, Table 3). The gene discussed is PON1; the disease is nasopharyngeal carcinoma.