Nevertheless, several studies have documented a blunted cortisol response to tetracosactide in hyperthyroid Graves’ disease, which would be consistent with the effects of anti‐ACTH antibodies in these patients.27, 28 It is also well known that patients suffering from one autoimmune disease are susceptible to development of a second autoimmune condition, manifesting either as overt disease following pathological destruction of self‐tissue or as the presence of circulating autoantibodies alone. Here, POMC is linked to Graves disease.