To analyze the prognostic value of combining TGF-β1 and ELF levels for HCC, we divided patients into the following four groups, such as: TGF-β1 high expression- ELF high expression group, TGF-β1 low expression- ELF high expression group, TGF-β1 high expression - ELF low expression group, TGF-β1 low expression- ELF low expression group. Here, SPTBN1 is linked to hepatocellular carcinoma.