A significant decrease in the expression of myophosphorylase and several of the glycolytic enzymes was observed in muscular dystrophies (Duchenne Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type 2C (LGMD2C), Neuronal Ceroid Lipofuscinosis and patients affected of intensive care unit myopathy) (Table 1 and Additional file 4: Figure S4). Here, HK1 is linked to myopathy.