Brew and colleagues found an AD-like pattern of CSF Aβ1-42, t-tau and p-tau concentrations in mild to moderate HAND (N = 87; 46 AIDS-dementia complex (ADC) stage 1; 41 ADC stage 2; age: μ = 42; SD = 11) consistent with that seen in AD [4]. This evidence concerns the gene MAPT and Alzheimer disease.