The NF-κB variant rs7665090 was shown to be associated with patients belonging to a diffuse cutaneous phenotype (dcSSc) (OR = 1.28, 95% CI 1.11 to 1.47, Padj = 0.003) and also with the PF subset (OR = 1.24, 95% CI 1.09 to 1.41, Padj = 0.004) (Table 3). This evidence concerns the gene NFKB1 and pemphigus foliaceus.