Furthermore, parathyroid hormone-like hormone (PTHLH) which encodes parathyroid hormone-related protein (PTHrP) could play a character in the pathogenesis of oral squamous cell carcinoma by interfering cell proliferation and cell cycle, and the protein levels of PTHrP might potentially serve as a prognostic indicator for the evaluating patients with HNSCC [61]. This evidence concerns the gene PTHLH and oral cavity squamous cell carcinoma.