To explore the difference between non-malignant reference tissue and neoplastic cells, we further investigated the methylation status of SOX11 in 42 cell lines (Table 1) representing a wide range of human tumors with subgroups known to express SOX11, including lymphoid malignancies (n=19), ovarian cancer (n=5), breast cancer (n=8), lung cancer (n=3), brain cancers (n=5) and neuroblastoma (n=2). This evidence concerns the gene SOX11 and neuroblastoma.