In order to verify the role played by SREBP1 in the CAF-triggered effect on SCD1 expression in tumor cells, the desaturase protein levels were determined by Western blotting in MCF-7 and MDA-MB-231 cells treated with CAF-CM in the presence of 20 μM Fatostatin, an inhibitor of SREPB activation. This evidence concerns the gene SCD and neoplasm.