After adjusted for age, gender, smoking, diabetes mellitus, hypertension, Lp(a), LDL-C, HDL-C, apoA and statins, Lp-PLA2 level was still independently associated with severity of CAD, with odd ratio (OR) of 1.055 (AMI versus control group, 95% confidence interval (CI) 1.021-1.090, P < 0.05). This evidence concerns the gene PLA2G7 and Hypertension.