CD4 and infection: The respective overall effector/memory CD4 T cells (i.e. CD4+ IFN-γ+/- cells) proportions under both long- and short-term conditions are shown in S4B Fig The relative contribution of Tcm, Tem and effector CD4+ T cells in the response to PPDb (Fig 3B) and to rESAT-6:CFP10 (Fig 3C) remained the same over the course of infection (i.e., at 6, 8, and 12 weeks after challenge).