APOC3 and obesity due to melanocortin 4 receptor deficiency: Despite insufficient sample size, the observations from this study ascertain the established findings and association between the FTO rs9939609 A allele with obesity in previous reported studies.25 However, MS is a multifactorial and complex metabolic disorder, and only a few of the reported genes, such as PPARG and APOC3, have been reproduced in more than one study sample.26 Apart from the requirement to reproduce and replicate the SNP at FTO gene in other larger study samples, the cellular and molecular mechanics causing this linkage also needs to be researched.