FTO and obesity due to melanocortin 4 receptor deficiency: The discovery of FTO gene and its researched associations is considered a milestone of Human genome studies.19FTO gene has been extensively investigated because of its association with obesity, cardiovascular risk factors and MS.8Studies from Asia and specifically from South East Asia reported the association of FTO gene with obesity and associated risk factors.1,3 Variant of FTO gene at rs9939609 is also found to be associated with patients with type 2 diabetes in Europeans and South Asians.20 The association of patients with obesity has been replicated in a Pakistani study.21